SCLC-21H

Zellname

Beschreibung

Bestell-Nr.

Einheit

Preis, Euro

SCLC-21H

Humane Lungenkarzinom (kleinzellig) Zell-Linie

300225

cryovial

265,00

SCLC-21H

Humane Lungenkarzinom (kleinzellig) Zell-Linie

330225

vital

335,00



Designation:SCLC-21H
Organism:Homo sapiens (human)
Age/Stage:45 years of age
Gender:male
Tissue:Lung (pleural effusion)
Morphology:suspended, sheets and chains with loose inercellular contact
Celltype:Small-cell lung carcinoma
Growth Properties:Suspension
Culture Medium:DMEM medium supplemented with 2 mM L-glutamine and 10% fetal bovine serum.
Subculturing:Transfer appropriate amounts of cell suspension into new cell culture flasks containing fresh media.
Split Ratio:A ratio of 1:2 to 1:4 is recommended
Doubling Time:45 h
Freeze Medium:CM-1 (CLS ∙ Cell Lines Service)
Sterility:Tests for mycoplasma, bacteria and fungi were negative
Tumorigenic:yes, in nude mice
Oncogene:c-myc amplification present, c-myc expression high
Karyotype:Modal chromosome number 42/43, range 39-44. Chromosome deletion 3p.


References:

Bepler G et al. Characterization of two cell lines with distinct phenotypes established from a patient with small cell lung cancer. Cancer Res 47: 1883-91, 1987. PMID: 3028617
Heidtmann HH et al. Synthesis and Secretion of Plasminogen Activators and Plasminogen Activator Inhibitors in Cell Lines of Different Groups of Human Lung Tumors. Cancer Res 49: 6960-65, 1989.
Verbeeck MA et al. Expression of the vasopressin and gastrin-releasing peptide genes in small cell lung carcinoma cell lines. Pathobiology 60: 136-42, 1992. PMID: 1320893
Schreiber G et al. Molecular characterization of the human delta opioid receptor in lung cancer. Anticancer Res 18:1787-92, 1998. PMID: 9673405
Characterization of two cell lines with distinct phenotypes

 

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