STRETCHING of CELLS – INNOVATIVE and EASY
Several cell types of our organism, for example endothelial tissue cells, osteoblasts and epithelium cells, are exposed to mechanical stress. To deal with this mechanical stress, elasticity of the cell membrane is required.
In a standard culture these as well as other cells proliferate statically; however, this does not represent their natural growth in vivo.
Several studies show that these cells produce physiological quantities of substances specific for each cell type, and undergo morphological changes if exposed to cell surface stretching.
The S1 Cell Stretcher reproduces the physiological conditions in an easy manner. It is constructed stably and is sold to a favorable price.
The system consists of three parts: the pressure chamber, the power supply, and the stretching unit. The pressure chamber connected to the power supply generates cyclic pressure changes above and below the atmospheric pressure.
These pressure variations are relayed to the stretching unit via small tubings and produce an up- and down deformation of the flexible membrane of the six-well-plate resulting in stretching of the cells.
The inhomogeneous stretch profile over the membrane represents the most innovative detail of the S-1 Stretching Apparatus.
Mechanical Stress
Endlich et al. (1.9 MB)